This article will focus on recent advances in AMT and expand to cover its clinical uses beyond the ocular surface. Owing to space limitations, it has not been possible to cite all of the relevant publications. To be familiar with AMT uses for ocular surface reconstruction, readers are encouraged to consult other reviews. The majority of the studies testify to the clinical efficacy of AMT in gearing adult wound healing toward regeneration with minimal inflammation and scarring, suggesting that AM, like fetal tissue, carries a similar feature that may not only promote healing but also facilitate regeneration. Specifically, over the last 15 years, over 800 peer-reviewed publications have been put forward describing how AM transplantation (AMT) has been performed to treat a variety of ophthalmic indications ( Figure 2). When properly processed and preserved, preferably using the patented cryopreservation method, this semitransparent and resilient tissue has been successfully used as a surgical graft for a wide range of ophthalmic indications (for reviews see ). Amniotic membrane is fused with (6) the cytotrophoblast layer of the chorion. Histologically, amniotic membrane is composed of (1) a monolayer of simple epithelium with a basement membrane, and an avascular stroma, which can further be subdivided into (2) compact, (3) fibroblast, (4) sponge and (5) reticular layers. The placental membrane consists of the outer chorion (depicted in dark grey) and the inner amniotic membrane (depicted in light grey). "A useful addition to clinical pediatric endocrinology and of interest also to geneticists.The amniotic membrane in the uterus and its histology No matter your disease(s) of interest, its molecular/cellular basis is covered in this mutiauthored book. ".cuts a wide and deep swath through the basic biology and pathology of the disorders deal with in the clinic every day.
The rest of the text treats the molecular genetics of thyroid cancer, hypophosphatemic rickets, and inherited diabetes insipidus."-SciTech Book News The pathophysiology of diabetes mellitus is the subject of two chapters. Steroid hormones, sexual development, and mineralacortoid action are discussed in the next five chapters (including a review of the first human case of estrogen receptor defects). The first seven chapters focus on the regulation of growth and the growth hormone/prolactin/placental lactogen gene family. overview the most rapidly developing areas of advances in molecular advances and their applications to the study, diagnosis, and treatment of pediatric endocrine disorders. Molecular and Cellular Pediatric Endocrinology offers today's clinicians and researchers not only the latest findings on endocrine disorders in their pediatric manifestations, but also highly practical insights into today's cutting-edge diagnostics, emerging treatment strategies, and powerful new therapeutics. Additional chapters examine the pathophysiology of insulin-dependent diabetes mellitus, the molecular genetics of thyroid cancer, the molecular basis of hypophosphatemic rickets, and inherited diabetes insipidus.
Topics range from the growth hormone/prolactin/placental lactogen gene family and their regulation of growth, to steroid hormones, sexual development, and mineral corticoid action. In Molecular and Cellular Pediatric Endocrinology, Stuart Handwerger, MD and a distinguished panel of clinicians and experts review the most significant recent developments in molecular and cellular biology, powerful advances that have produced new diagnostic methods and improved treatments for many pediatric endocrine diseases.
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